![]() Research indicates that vision and hearing loss is correlated with age-related cognitive decline, and with a higher risk of developing dementia due to Alzheimer’s disease. However, some of these changes can become pathological. Introduction: The occurrence of age-related vision changes is inevitable. ![]() 4School of Physical and Occupational Therapy, McGill University, Montréal, QC, Canada.3Department of Psychology, Université de Montréal, Montréal, QC, Canada.2Department of Psychology, Concordia University, Montréal, QC, Canada.1School of Optometry, Université de Montréal, Montréal, QC, Canada.doi:10.1212/WNL.Gabrielle Aubin 1 Natalie Phillips 2 Atul Jaiswal 1 Aaron Paul Johnson 2 Sven Joubert 3 Vanessa Bachir 1 Eva Kehayia 4 Walter Wittich 1,2,4 * Association of Digital clock drawing with PET amyloid and tau pathology in normal older adults. Digital Cognitive Assessments: Advancing cognitive testing. Presented at: 2023 Alzheimer’s Association International Conference June 16-20 Amsterdam, Netherlands. Comparative performance of the Digital Clock and Recall (DCR) test, Montreal Cognitive Assessment (MoCA), and Saint Louis University Mental Status (SLUMS) among patients in primary care. 3Ĭlick here for more coverage of AAIC 2023. Among CN participants with biomarkers, the DCTclock summary score and spatial reasoning subscores were associated with greater amyloid and tau burden and showed better discrimination (Cohen d = 0.76) between amyloid-ß-positive groups than the Preclinical Alzheimer Cognitive Composite (PACC) assessment. The study included 300 participants, 264 of whom were cognitively normal (CN) and 36 with a diagnosis of mild cognitive impairment (MCI) or early AD dementia. In 2021, research on DCTclock using participants from the Harvard Aging Brain Study was published, with findings showing that the digital clock-drawing test was effective in identifying the early changes in AD pathology in cognitively normal individuals. In addition, digital strategies included automated scoring and interpretation, fast online results, results tracking, and offer greater or comparable sensitivity in early stages of cognitive impairment relative to traditional methods. In comparison with other traditional paper-based measures, digital technologies like DCR and DCTclock require minimal training, are standardized and objective, and incorporate multilanguage support. Overall, the comparison between impaired DCR Scores (0-3) and impaired MoCA total score was strong, and even stronger in those with memory deficits on DCR Delayed Recall. READ MORE: Caregivers Perceived Reciprocity Reduces Behavioral Symptoms in Patients With Alzheimer DiseaseĪ receiver operating characteristic area under the curve analysis further revealed that the combination of DCR total score (0-5), DCTclock score (0-100), DCR Delayed Recall score (0-3), and age had the strongest ability to discriminate MoCA total score impairment (AUC =. When MoCA total scores were paired with low DCR Delayed Recall performance, concordance was increased to 81% (76 of 94). Impaired DCR scores of 0-3 and impaired MoCA total scores of less than 26 had a 76% concordance with each other, while the remaining 24% of patients with impaired DCR scores had normal MoCA total scores. In the comparison analysis between DCR and SLUMS, all 13 patients had Impaired DCR scores and SLUMS scores. Similarly, individuals considered Impaired, indicated by scores of 0-1, corresponded to MoCA total scores and MIS scores well-below cutoffs (21.20 and 9.61, respectively). Hammers, PhD, MS, associate professor of neurology at the Indiana University School of Medicine, results showed that borderline impairment on DCR corresponded to MoCA total scores and MoCA Memory Index Score (MIS) scores slightly below traditional cutoffs (23.65 and 11.65, respectively). An additional 13 patients whose DCR performance was borderline or indicative of cognitive impairment completed all 3 assessments, which included SLUMS. ![]() Presented at the 2023 Alzheimer’s Association International Conference (AAIC), held June 16-20, in Amsterdam, Netherlands, the study comprised of 114 participants aged at least 65 years who scored in the Borderline Cognitive Impaired or Cognitive Impaired categories on the CDR and completed the MoCA. Performance on the DCR was concordant with the other previously established measures as well. In a comparative study, findings showed that cognitive screening in primary care settings was faster using the Digital Clock and Recall (DCR) than other traditional tests like the Montreal Cognitive Assessment (MoCA) and St. ![]()
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